Point-to-point integration is an antipattern where integrations are made directly from one system to another. They are developed with the "best" technology of each era and deployed into a corner of a random server. Sometimes they are hosted in the integrated system itself.
Henry, the Heroic coder from the IT department, used to do these with PHP, after which Cora, the Cowboy coder, continued with his Python scripts. Both scheduled their scripts with separate Cron instances somewhere in the jungle of different servers. Over the years, tens or hundreds of integration point-to-point scripts accumulate. Think of one such script that executes a single data stream as one spaghetti ribbon. The consequence of this kind of hero integration is a network resembling a heap of spaghetti, to which making changes has unforeseen consequences. Also, changing one system from this spaghetti is surprisingly tricky. The integration links to and from the replaced system break and not all of the connections are even known — as Henry and Cora were notoriously lazy documenters of their code. And most importantly - centralized control of data flows is impossible.